"Upstate" is an interesting term that few residents north of Middletown or Poughkeepsie" use. Residents in Syracuse might refer to their part of the state as Central New York. Utica-Rome calls itself the Mohawk Valley, the Adirondacks are often called the North Country, Alabany "the Capital District."
The area from Rochester west is called Western New York, occasionally the Niagara Frontier, which is Old School. And as has been notedin this thread, "Upstate" is predominantly dedicated to the Yankees. AAA ball from Syracuse to Rochester to Buffalo once was all about the American League. The National League Mets were once briefly affiliated with the Biffalo Bisons. It wasn't a good fit.
The best years of the Bisons (then briefly in the American Association) were as an affiliate of the Cleveland Indians. The Bisons are now back at home in the International League, where they were a legacy member.
In the '80s, the Bisons slipped all the way down to the Class AA Eastern League, with the Pirates and Indians as their big-league clubs. The building of Pilot Field was the impetus for Buffalo's return to AAA and its amazing attendance boom. I remember seeing the Bisons' team bus in the parking lot at New Britain Stadium, with "Here come the batterin' Bisons" on the front, and "There go the batterin' Bisons" on the back, accompanied by the team logo of a scowling, snorting bison getting ready to take a swing. They were the only visiting team with a customized bus. The others bore the names and logos of various charter transportation companies in those teams' cities. That was an indication to me that Bisons management had bigger things than the Eastern League, with its trips to Waterbury, New Britain and Albany, in mind.