I'm not a computer/Adobe expert...nor do I play one on the radio, but here's a thought or two.
Go to your OPTIONS then SETTINGS and then SYSTEM check your "Wave Cache". Mine is set to 16384 and I'm having no problems. Or maybe change your "temporary folders" setting. I'm sure you've already checked, but double check to see if you have enough space on the hard drive you're recording too. The only time I've had a problem that you are having is when my computer had run out of space. I made some back ups deleted the saved files and then everything worked again.
Or it maybe a Windows setting that someone screwed with perhaps the cache files in windows were changed without you knowing. Like I said I am NO expert, but it does sound like a "space available" problem.
If anybody else has ideas...speak up!
Terry