Wow that's a tough call. I really like the DX-50 in fact, I even chose to buy several of them over the Nautel equivalent back in the day, but agree that the DX-50 is getting long in the tooth. Not sure whether, or for how long the most recent owners of GatesAir will continue supporting the DX-series.
Since Nautel is really the only other newer option for AM since Harris/GatesAir and BE got out of the AM and higher power sales, I'd hold my nose and go with the Nautel. The reason I'd hold my nose is (and I'll likely take some heat for these comments) the newer Natuel transmitters are not built as robustly as they used to be, and like a lot of companies, support has gone further to the backseat. For example, multiple switching power supplies are great when one fails, but they really aren't field repairable anymore. In spite of finding the manufacturer of the power supplies used in Nautel transmitters, they won't sell you a power supply directly. Instead, Nautel marks the price up 100% over buying direct. To me, that's just greed and not supporting your customer.
One other thing that bothers me, is the sexy touch screens and UI on the front panel. There was an issue a few years ago where some touch screens would have a mind of their own, and just shut down the transmitter. And if the backlight on that screen eventually goes away, you're completely blind as to what's going on with the box, or being able to see for control. Here I am sounding old school, but give me some on-off buttons and LED indicators under the flat panel display so I can at least turn the thing on or off.
Good luck!