When you think about it, it's hard to advertise insect sprays because you may have to show bugs, etc. that tend to make viewers shy away. However, Raid (owned by Johnson's Wax), smartly went to animation beginning in the early days of TV to sell its product. The ending portion of one of those still remains one of my favorites. It's from approximately 1965.
At the end of the commercial, a bug is located next to what appears to be a telephone although it is covered in mist. The phone rings and the bug picks it up and says, "hello". With that, the mist-like phone changes into a can of Raid and sprays the bug and you hear a voice saying, "good-bye".
I've looked and looked for this specific TV commerical on the internet. There are some Raid commercials there, but not this one. It's been years, but I'd like to see it again.