I don't like "best ofs" for topical shows at ALL.
For service/advice shows, I don't care.
Local talker WNIR/100.1 here never, ever runs "Best of" shows. When the main weekday/daytime hosts are gone, there's usually a live sub (Bob Earley, usually, who now hosts his own weekend show, though former newspaper columnist Stuart Warner has filled in once or twice, and afternoon newsman Phil Ferguson has also filled in). When morning co-host Stan Piatt was on vacation recently, the other three members of the show (Maggie Fuller, newsman Jim Midock and sports guy Steve French) just went without him.
When evening host Tom Erickson is off, the station plugs in a syndicated show to "fill-in" for him. TRN's Laura Ingraham and Michael Savage have been used recently...both shows air on sister one-lung daytime talker WJMP/1520 Kent. Ditto when Earley is off his Saturday/Sunday show.
As far as Rush goes, they pretty much do it right...with guest hosts most of the time, and best of shows on major holidays.