Yes, for just $45, KQED listeners who pledge in advance of the start of the May pledge drive will gain access to a special stream, which will be void of any pledge breaks during programming.
http://www.bizjournals.com/sanfrancisco/blog/2011/04/kqed-way-to-opt-out-of-pledge-drives.html
http://www.bizjournals.com/sanfrancisco/blog/2011/04/kqed-way-to-opt-out-of-pledge-drives.html