They are very much in line with the politics and attitude of Southern California (although none of the hosts like Gov. Newsom very much). It also helps that they let go of serious discussions and topics after 6pm, and give listeners much needed comedic relief with Tim Conway Jr.KFI does seem to be very centrist on many issues, especially most of the social ones (you will not hear a lot of anti-abortion rhetoric, for example). They mostly have conservative points of view on fiscal issues (taxes/government waste) and immigration.
I think also there is also a pretty strong anti-establishment streak, which means they are often bumping into the left-wing leadership and policies of LA County and the State of California.