"Boston's claim to fame as “The Hub of the Universe” was the work of none other than Oliver Wendall Holmes. In 1858, Holmes referred to the Massachusetts State House Building as the “Hub of the Solar System”. Bostonians liked the sound of that so the nickname, with minor modifications, stuck. When the now defunct Filenes built their flagship store at the corner of Washington and Summer Streets, a fancy bronze marker was installed to forever give credence to the name."
Or so says someone on the internets.