Yea that's what I've been using - CAT5 and CAT6. Right now I's sitting here listening to a Fostex 6301B of the PGM from main control, and it's run from the rack room about 150 feet away, over four hops, two patchbays, and wall wiring into my office, and it sounds clear as if I was in the studio.
Don't forget the StudioHub™ system uses CAT5/6 cable, and it seems to work just fine. I've never heard anything about it being a problem. In fact, I used some spare StudioHub XLR-to-RJ45 adapters to wire the monitor hookup I speak of above. I used the CAT6 building wiring right to the wall jack in my office, and a 20-foot Ethernet cable with one end hacked off and replaced by an XLR connector on the blue pair.
And, to widen the discussion from my original question about unshielded interconnect wire, one might ask, what is it exactly? It looks like just a single pair of what's in a CAT5/6 cable, right? Well, as I understand it, "it's all in the twist", which is a phrase I saw somewhere once. Interconnect wire and 10mbps Ethernet is CAT3, 100mbps is CAT5, and 1000mbps is CAT6, each with an increasing tightness & precision of the twist, the purpose being more perfect nulling. And they are all backwards compatible, so CAT3 is for audio, so CAT5/6 should work for audio too, but have cleaner transmission.
I have considered that using shielded CAT5/6 between patchbays and wall jacks, with the shields all centrally grounded and not passed through to the jacks would be an excellent happy-medium between shielded and not.
I have to say that if we ever remodel or move this place any time soon, and we're not all-digital by then, I will wire EVERYTHING with CAT6 - even the audio between studios & racks. Unless by then doing everything with fiber is cost effective, but that would requires us to be digital, and by then if we're not 100% digital behind the mics & cans, it'd just be kinda silly.