A radio company in Tampa could release a 80's and 90's Classic Alternative channel. 98.7 or 97x will be good. Jangle Pop, New Wave, Punk Rock and music from Independent Labels is where you start. Bauhaus, R.E.M, The Clash, X, Echo and The Bunnymen, Morrissey, The B-52's and Depeche Mode will be staple artists. You could also play music from Elvis Costello, The Velvet Underground and Jesus and Mary Chain.
I would focus on the 80's mainly due to the 90's Grunge burn-out. The 90's I would focus on would be Toad the Wet Sprocket, Weezer, Electronic, Citizen King, They Might Be Giants, Barenaked Ladies.
70'S could be stuff from David Bowie, The Ramones, Iggy Pop, Buzzocks, Joan Jett, The Vibrators and Patti Smith. Punk Rock will be the key.
Heck 102.5 could have this format on weekends.